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Gene Expression Literature Summary
Assay
Age
In situ reporter (knock in)
Postnatal

6 matching records from 6 references.

Summary by Gene and Reference: Number indicates the number of results matching the search criteria recorded for each reference.
* Indicates detailed expression data entries available
Dll4  delta like canonical Notch ligand 4   (Synonyms: Delta4)
Results  Reference
1*J:99531 Benedito R, Duarte A, Expression of Dll4 during mouse embryogenesis suggests multiple developmental roles. Gene Expr Patterns. 2005 Aug;5(6):750-5
1J:94740 Gale NW, Dominguez MG, Noguera I, Pan L, Hughes V, Valenzuela DM, Murphy AJ, Adams NC, Lin HC, Holash J, Thurston G, Yancopoulos GD, Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development. Proc Natl Acad Sci U S A. 2004 Nov 9;101(45):15949-54
1J:258489 Herman AM, Rhyner AM, Devine WP, Marrelli SP, Bruneau BG, Wythe JD, A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse. Biol Open. 2018 Feb 8;:bio026799
1J:325252 Hou S, Li Z, Dong J, Gao Y, Chang Z, Ding X, Li S, Li Y, Zeng Y, Xin Q, Wang B, Ni Y, Ning X, Hu Y, Fan X, Hou Y, Li X, Wen L, Zhou B, Liu B, Tang F, Lan Y, Heterogeneity in endothelial cells and widespread venous arterialization during early vascular development in mammals. Cell Res. 2022 Apr;32(4):333-348
1J:125893 Suchting S, Freitas C, le Noble F, Benedito R, Breant C, Duarte A, Eichmann A, The Notch ligand Delta-like 4 negatively regulates endothelial tip cell formation and vessel branching. Proc Natl Acad Sci U S A. 2007 Feb 27;104(9):3225-30
1J:327590 Xia S, Menden HL, Townley N, Mabry SM, Johnston J, Nyp MF, Heruth DP, Korfhagen T, Sampath V, Delta-like 4 is required for pulmonary vascular arborization and alveolarization in the developing lung. JCI Insight. 2021 Apr 8;6(7)

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/23/2024
MGI 6.23
The Jackson Laboratory